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Graduate School of Biomedical Sciences

Farha Mithila

Research Technician

Farha Mithila

Farha Mithila

Research Technician

Education: 
BS, Biochemistry University of Massachusetts - Boston, Boston, MA
Research synopsis: 

Sickle Cell Disease (SCD) is a genetic hematologic disorder characterized by sickle-shaped red blood cells (RBC). Sickle cell disease is a debilitating condition affecting nearly 100,000 people in the USA and millions of people in the world, particularly the population of sub-Saharan Africa. Our previous studies indicate that calpains, a family of calcium-dependent cysteine proteases, play an important role in regulating RBC shape and membrane properties. I am investigating the role of calpains in SCD using genetically modified mouse models. These studies may ultimately lead to the development of calpain inhibitors as potential therapeutics for sickle cell disease.

Advisor: