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Graduate School of Biomedical Sciences

Recent Publications from the Schaffhausen Lab

Denis D, Rouleau C, Schaffhausen BS. 2017. A transformation-defective polyomavirus middle T antigen with a novel defect in PI3 kinase signaling. J Virol. 91: pii: e01774-16. Abstract

Rouleau C, Pores Fernando AT, Hwang JH, Faure N, Jiang T, White EA, Roberts TM, Schaffhausen BS. 2016. Transformation by Polyomavirus middle T antigen involve a unique bimodal interaction with the Hippo effector YAP. J Virol. 90: 7032-7045. Abstract

White EA, Kramer RE, Hwang JH, Pores Fernando AT, Nana N, Hahn WC, Roberts TM, Schaffhausen BS, Livingston DM, Howley PM. 2014. Papillomavirus E7 oncoproteins share functions with Polyomavirus small T antigens. J Virol. 89: 2857-2865. Abstract

Hwang JH, Pores Fernando AT, Faure N, Andrabi S, Hahn WC, Schaffhausen BS, Roberts TM. 2014. Polyoma small T antigen interacts with YES-Associated Protein (YAP) to regulate cell survival and differentiation. J Virol. 88: 12055-12064. Abstract  (Correction: J Virol. 89: 6971)

Utermark T, Schmit F, Lee SH, Gao X, Schaffhausen BS, Roberts TM. 2014. The PI3K isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type. J Virol. 88: 10673-10679. Abstract

Pores Fernando AT, Andrabi S, Cizmecioglu O, Zhu C, Livingston DM, Higgins JM, Schaffhausen BS, Roberts TM. 2014. Polyoma small T antigen triggers cell death via mitotic catastrophe. Oncogene 34: 2483-2492. Abstract

Banerjee P, Dejesus R, Gjoerup O, Schaffhausen BS. 2013. Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA. PLoS Pathog. 9: e1003725. Abstract

Harrison C, Jiang T, Banerjee P, Meinke G, D'Abramo CM, Schaffhausen B, Bohm A. 2013. Polyomavirus large T-antigen binds symmetrical repeats at the viral origin in an asymmetrical manner. J Virol. 87: 13751-13759. Abstract

Hwang JH, Jiang T, Kulkarni S, Faure N, Schaffhausen BS. 2013. Protein phosphatase 2A isoforms utilizing Aβ scaffolds regulate differentiation through control of Akt. J Biol Chem. 288: 32064-32073. Abstract

Miao B, Skidan I, Yang J, You Z, Fu X, Famulok M, Schaffhausen B, Torchilin V, Yuan J, Degterev A. 2012. Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene 31: 4317-4332. Abstract