Skip to main content
Graduate School of Biomedical Sciences

Recent Publications from the Kritzer Lab

Cerulli RA, Kritzer JA. 2019. Phosphotyrosine isosteres: past, present and future. Org Biomol Chem. 28. doi: 10.1039/c9ob01998g. Abstract

Cerulli RA, Kritzer JA. 2019. Stringing together a universal influenza antibody. Biochemistry Epub ahead of print. Abstract

Cummings AE, Miao J, Slough DP, McHugh SM, Kritzer JA, Lin YS. 2019.  β-branched amino acids stabilize specific conformations of cyclic hexapeptides. Biophys J. Epub ahead of print. Abstract

Peraro L, Kritzer J. 2018. Getting in: Emerging methods and design principles for cell-penetrant peptides. Angew Chem Int Ed Engl. Epub ahead of print. Abstract

Slough DP, McHugh SM, Cummings AE, Dai P, Pentelute BL, Kritzer JA, Lin YS. 2018. Designing well-structured cyclic pentapeptides based on sequence-structure relationships. J Phys Chem B 122: 3908-3919. Abstract

Kritzer JA, Freyzon Y, Lindquist S. 2018. Yeast can accommodate phosphotyrosine: v-Src toxicity in yeast arises from a single disrupted pathway. FEMS Yeast Res. Epub ahead of print. Abstract

Kamens AJ, Mientkiewicz KM, Eisert RJ, Walz JA, Mace CR, Kritzer JA. 2018. Thioether-stapled macrocyclic inhibitors of the EH domain of EHD1. Bioorg Med Chem. 26: 1206-1211. Abstract

Siegert TR, Bird M, Kritzer JA. 2017. Identifying loop-mediated protein-protein interactions using LoopFinder. Methods Mol Biol. 1561: 255-277. Abstract

Kritzer JA. 2016. Stapled peptides: How to be quick on the uptake. Nat Chem Biol. 12: 764-765. Abstract

Peraro L, Siegert TR, Kritzer JA. 2016. Conformational restriction of peptides using dithiol bis-alkylation. Methods Enzymol. 580:303-332. Abstract

Charkoudian LK, Sampson NS, Kumar K, Kritzer JA 2016. Designing convergent chemistry curricula. Nat Chem Biol. 6: 382-386.  Abstract

Quartararo JS, Eshelman MR, Peraro L, Yu H, Baleja JD, Lin YS, Kritzer JA. 2014. A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. Bioorg Med Chem. 22: 6387-6391.  Abstract

Eshelman MR, Aldous AR, Neupane KP, Kritzer JA. 2014. Solution structure of a designed cyclic peptide ligand for nickel and copper ions. Tetrahedron 70: 7651-7654.  Abstract

Gavenonis J, Sheneman BA, Siegert TR, Eshelman MR, Kritzer JA. 2014. Comprehensive analysis of loops at protein-protein interfaces for macrocycle design. Nat Chem Biol. 10: 716-722.  Abstract

Kamens AJ, Eisert RJ, Corlin T, Baleja JD, Kritzer JA. 2014. Structured cyclic peptides that bind the EH domain of EHD1. Biochemistry 53: 4758-4760.  Abstract

Gavenonis J, Jonas NE, Kritzer JA. 2014. Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix. Bioorgan Med Chem. 22: 3989-3993.  Abstract

Neupane KP, Aldous AR, Kritzer JA. 2014. Metal-binding and redox properties of substituted linear and cyclic ATCUN motifs. J Inorgan Biochem. 139: 65076.  Abstract

Choudary SK, Qiu J, Plaut AG, Kritzer JA. 2013. Versatile substrates and probes for IgA1 protease activity. Chembiochem. 14: 2007-2012.  Abstract

Neupane KP, Aldous AR, Kritzer JA. 2013. Macrocyclization of the ATCUN motif controls metal binding and catalysis. Inorgan Biochem. 52: 2729-2735.  Abstract

Bock JE, Gavenonis J, Kritzer JA. 2013. Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraints. ACS Biochem 8: 488-499.  Abstract

Kritzer JA. 2012. The secret of MIM: a novel, MCL-1-specific small molecule. Chem Biol. 19: 1082-1083.  Abstract

Quartararo JS, Wu P, Kritzer JA. 2012. Peptide bicycles that inhibit the Grb2 SH2 domain. Chembiochem 13: 1490-1496.  Abstract