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Graduate School of Biomedical Sciences

Recent Publications from the Friesel Lab

Yang X, Gong Y, He Q, Licht JD, Liaw L, Friesel RE. 2017. Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits. J Biol Chem. 119: 3267-3279. Abstract

Caron JM, Ames JJ, Contois L, Liebes L, Friesel R, Muggia F, Vary CP, Oxburgh L, Brooks PC. 2016. Inhibition of ovarian tumor growth by targeting the HU177 cryptic collagen epitope. Am J Pathol. 186: 1649-1661. Abstract

Jing H, Liaw L, Friesel R, Vary C, Hua S, Yang X. 2016. Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells. Cancer Cell Int. 16:19. Abstract

He Q, Gong Y, Gower L, Yang X, Friesel RE. 2016. Sef regulates epithelial-mesenchymal transition in breast cancer cells. J Cell Biochem. 117: 2346-2356. Abstract

Liaw L, Prudovsky I, Koza RA, Anunciado-Koza RV, Siviski ME, Lindner V, Friesel RE, Rosen CJ, Baker PR, Simons B, Vary CP. 2016. Lipid profiling of in vitro cell models of adipogenic differentiation: Relationships with mouse adipose tissues. J Cell Biochem. 117: 2182-2193. Abstract

Ames JJ, Contois L, Caron JM, Tweedie E, Yang X, Friesel R, Vary C, Brooks PC. 2015. Identification of an endogenously generated cryptic collagen epitope (XL313) that may selectively regulate angiogenesis by an integrin Yes-associated protein (YAP) mechano-transduction pathway. J Biol Chem. 291: 2731-2750. Abstract

Muthukrishnan SD, Yang X, Friesel R, Oxburgh L. 2015. Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells. Nat Commun. 6: 10027. Abstract

Yang X, Liaw L, Prudovsky I, Brooks PC, Vary C, Oxburgh L, Friesel R. 2015. Fibroblast growth factor signaling in the vasculature. Curr Atheroscler Rep. 17: 509.  Abstract

Contois LW, Akalu A, Caron JM, Tweedie E, Cretu A, Henderson T, Liaw L, Friesel R, Vary C, Brooks PC. 2014. Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo. Angiogenesis 18: 31-46. Abstract

Marks PC, Preda M, Henderson T, Liaw L, Lindner V, Friesel RE, Pinz IM. 2013. Interactive 3D analysis of blood vessel trees and collateral vessel volumes in magnetic resonance angiograms in the mouse ischemic hindlimb model. Open Med Imaging 7: 19-27.  Abstract

He Q, Yang X, Gong Y, Kovalenko D, Canalis E, Rosen CJ, Friesel RE. 2016. Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity. J Bone Miner Res. 29: 1217-1231.  Abstract

Poole A, Knowland N, Cooper E, Cole R, Wang H, Booth L, Kacer D, Tarantini F, Friesel R, Prudovsky I. 2014. Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation. J Cell Biochem. 115: 874-888.  Abstract

Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE. 2013. Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis 16: 861-875.  Abstract

Yang X, Gong Y, Tang Y, Li H, He Q, Gower L, Liaw L, Friesel RE. 2013. pry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling. PLoS One 8: e58746. Abstract

Contois LW, Nugent DP, Caron JM, Cretu A, Tweedie E, Akalu A, Liebes L, Friesel R, Rosen C, Vary C, Brooks PC. 2012. Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis. J Biol Chem. 287: 1779-1789. Abstract

Tang Y, Yang X, Friesel RE, Vary CP, Liaw L. 2011. Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells. J Vasc Res. 48: 485-494. Abstract

Brown AC, Adams D, de Caestecker M, Yang X, Friesel R, Oxburgh L. 2011. FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development. Development. 138: 5099-5112. Abstract

Kacer D, McIntire C, Kirov A, Kany E, Roth J, Liaw L, Small D, Friesel R, Basilico C, Tarantini F, Verdi J, Prudovsky I. 2011. Regulation of nonclassical fgf1 release and fgf-dependent cell transformation by CBF1-mediated notch signaling. J Cell Physiol., 226: 3064-3075. Abstract