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Graduate School of Biomedical Sciences

Recent Publications from the Brooks Lab

Cao L, Weetall M, Bombard J, Qi H, Arasu T, Lennox W, Hedrick J, Sheedy J, Risher N, Brooks PC, Trifillis P, Trotta C, Moon YC, Babiak J, Almstead NG, Colacino JM, Davis TW, Peltz SW. 2016. Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform. PLoS One. 11: e0168366. Abstract

Caron JM, Ames JJ, Contois L, Liebes L, Friesel R, Muggia F, Vary CP, Oxburgh L, Brooks PC. 2016. Inhibition of Ovarian Tumor Growth by Targeting the HU177 Cryptic Collagen Epitope. Am J Pathol. 186: 1649-1661. Abstract

Ames JJ, Henderson T, Liaw L, Brooks PC. 2016. Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model. Methods Mol Biol. 1406: 255-269. Abstract

Ames JJ, Contois L, Caron JM, Tweedie E, Yang X, Friesel R, Vary C, Brooks PC. 2016. Identification of an Endogenously Generated Cryptic Collagen Epitope (XL313) That May Selectively Regulate Angiogenesis by an Integrin Yes-associated Protein (YAP) Mechano-transduction Pathway. J Biol Chem. 291: 2731-2750. Abstract

Contois LW, Akalu A, Caron JM, Tweedie E, Cretu A, Henderson T, Liaw L, Friesel R, Vary C, Brooks PC. 2015. Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo. Angiogenesis 18: 31-46. Abstract

Duarte CW, Murray K, Lucas FL, Fairfield K, Miller H, Brooks P, Vary CP. 2014. Improved survival outcomes in cancer patients with hereditary hemorrhagic telangiectasia. Cancer Epidemiol Biomarkers Prev. 23: 117-125.  Abstract

Favreau AJ, Vary CP, Brooks PC, Sathyanarayana P. 2014. Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia. Cancer Med. 3: 265-272.  Abstract

Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE. 2013. Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis 16: 861-875.  Abstract

Rosenwasser AM, Fixaris MC, Crabbe JC, Brooks PC, Ascheid S. 2013. Escalation of intake under intermittent ethanol access in diverse mouse genotypes. Addict Biol. 18:496-507. Abstract

Contois LW, Nugent DP, Caron JM, Cretu A, Tweedie E, Akalu A, Liebes L, Friesel R, Rosen C, Vary C, Brooks PC. 2012. Insulin-like growth factor binding Protein-4 differentially inhibits growth factor-induced angiogenesis. J Biol Chem. 287: 1779-1789. Abstract

Romero D, O'Neill C, Terzic A, Contois L, Young K, Conley BA, Bergan RC, Brooks PC, Vary CP. 2011. Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res. 71: 3482-3493. Abstract