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Graduate School of Biomedical Sciences

Recent Publications from the Blanton Lab

Blanton RM. 2019. cGMP signaling and modulation in heart failure. J Cardiovasc Pharmaol. Epub ahead of print. Abstract

Blanton RM Jr, Carrillo-Salinas FJ, Alcaide P. 2019. T Cell recruitment to the heart: friendly guests or unwelcome visitors? Am J Physiol Heart Circ Physiol. Epub ahead of print. Abstract

Richards DA, Aronovitz MJ, Calamaras TD, Tam K, Martin GL, Liu P, Bowditch HK, Zhang P, Huggins GS, Blanton RM. 2019. Distinct phenotypes induced by three degrees of transverse aortic constriction in mice. Sci Rep. 9: 5844. Abstract

Zhang Y, Welzig CM, Haburcak M, Wang B, Aronovitz M, Blanton RM, Park HJ, Force T, Noujaim S, Galper JB. 2019. Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice. PLoS One 14: e0215213. Abstract

Ledoux T, Aridgides D, Salvador R, Ngwenyama N, Panagiotidou S, Alcaide P, Blanton R, Perrin MA. 2018. Trypanosoma cruzi neurotrophic factor facilitates cardiac repair in a mouse model of chronic Chagas disease. J Pharmacol Exp Ther. Epub ahead of print. Abstract

Calamaras TD, Baumgartner RA, Aronovitz MJ, McLaughlin AL, Tam K, Richards DA, Cooper CW, Li N, Baur WE, Qiao X, Wang GR, Davis RJ, Kapur NK, Karas RH, Blanton RM Jr. 2018. Mixed lineage kinase 3 (MLK3) prevents cardiac dysfunction and structural remodeling with pressure overload. Am J Physiol Heart Circ Physiol. Epub ahead of print. Abstract

Blanton RM. 2017 What can haemodynamic profiles teach us about heart failure in the paediatric population? Eur Heat J. 38: 2910-2911. Abstract

Nevers T, Salvador AM, Velazquez F, Ngwenyama N, Carrillo-Salinas FJ, Aronovitz M, Blanton RM, Alcaide P. 2017. Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure. J Exp Med. 214: 3311-3329. Abstract

Morine KJ, Qiao X, Paruchuri V, Aronovitz MJ, Mackey EE, Buiten L, Levine J, Ughreja K, Nepali P, Blanton RM, Oh SP, Karas RH, Kapur NK. 2017. Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure. Cardiovasc Pathol. 31: 26-33. Abstract

Salvador AM, Moss ME, Aronovitz M, Mueller KB, Blanton RM, Jaffe IZ, Alcaide P. 2017. Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation. Physiol Rep. 5 (12).  Abstract

in H, Welzig CM, Aronovitz M, Noubary F, Blanton R, Wang B, Rajab M, Albano A, Link MS, Noujaim SF, Park HJ, Galper JB. 2017. QRS/T-wave and calcium alternans in a type I diabetic mouse model for spontaneous postmyocardial infarction ventricular tachycardia: A mechanism for the antiarrhythmic effect of statins. Hearth Rhythm 14: 1406-1416. Abstract

Morine KJ, Qiao X, Paruchuri V, Aronovitz MJ, Mackey EE, Buiten L, Levine J, Ughreja K, Nepali P, Blanton RM, Karas RH, Oh SP, Kapur NK. 2017. Heart Vessels 32: 628-636. Abstract

Salvador AM, Nevers T, Velázquez F, Aronovitz M, Wang B, Abadía Molina A, Jaffe IZ, Karas RH, Blanton RM, Alcaide P. 2016. Intercellular adhesion molecule 1 regulates left ventricular leukocyte infiltration, cardiac remodeling, and function in pressure overload-induced heart failure. J Am Heart Assoc. pii: e003126.  Abstract

Thoonen R, Giovanni S, Govindan S, Lee DI, Wang GR, Calamaras TD, Takimoto E, Kass DA, Sadayappan S, Blanton RM. 2015. Molecular screen identifies cardiac myosin-binding protein-C as a protein kinase G-Iα substrate. Circ Heart Fail. 8: 776-787. Abstract

Nevers T, Salvador AM, Grodecki-Pena A, Knapp A, Velazquez F, Aronovitz M, Kapur NK, Karas RH, Blanton RM, Alcaide P. 2015. Left ventricular T cell recruitment contributes to the pathogenesis of heart failure. Circ Heat Fail. 8: 776-787. Abstract

Parikh A, Wu J, Blanton RM, Tzanakakis ES. 2015. Signaling pathways and gene regulatory networks in cardiomyocyte differentiation. Tissue Eng Part B Rev. 21: 377-392. Abstract

Pruthi D, Khankin EV, Blanton RM, Aronovitz M, Burke SD, McCurley A, Karumanchi SA, Jaffe IZ. 2015. Exposure to experimental preeclampsia in mice enhances the vascular response to future injury. Hypertension 65: 863-870. Abstract

Sasaki H, Nagayama T, Blanton RM, Seo K, Zhang M, Zhu G, Lee DI, Bedja D, Hsu S, Tsukamoto O, Takashima S, Kitakaze M, Mendelsohn ME, Karas RH, Kass DA, Takimoto E. 2015. PDE5 inhibitor efficacy is estrogen dependent in female heart disease. J Clin Invest. 124: 2464-2471. Abstract

Zhang Y, Welzig CM, Picard KL, Du C, Wang B, Pan JQ, Kyriakis JM, Aronovitz MJ, Claycomb WC, Blanton RM, Park HJ, Galper JB. 2014. Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice. Diabetes 63: 2097-2113. Abstract