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Graduate School of Biomedical Sciences

Recent Publications from the Baleja Lab

Rana R, Shearer AM, Fletcher EK, Nguyen N, Guha S, Cox DH, Abdelmalek M, Wang Y, Baleja JD, Covic L, Kuliopulos A. 2019. PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease. Mol Metab. 29:99-113. Abstract

Silver RJ, Paczosa MK, McCabe AL, Balada-Llasat JM, Baleja JD, Mecsas J. 2019. Amino acid biosynthetic pathways are required for Klebsiella pneumoniae growth in immunocompromised lungs and are druggable targets during infection. Antimicrob Agents Chemother. 63(8). pii: e02674-18. Abstract

Powers JF, Cochran B, Baleja JD, Sikes HD, Zhang X, Lomakin I, Langford TF, Stein KT, Tischler AS. 2018. A unique model for SDH-deficient GIST: an endocrine-related cancer. Endocr Relat Cancer 25: 943-954. Abstract

Pattni BS, Jhaveri A, Dutta I, Baleja JD, Degterev A, Torchilin V. 2017. Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG. Int J Parm. 532: 149-156. Abstract

Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, Deik AA, Pierce KA, Scott JM, Clish CB, Smith DE, Weinberger A, Avnit-Sagi T, Lotan-Pompan M, Segal E, Taylor A. 2017. Proc Natl Acad Sci USA 114: E4472-E4481. Abstract

Hawver LA, Giulietti JM, Baleja JD, Ng WL. 2016. Quorum sensing coordinates cooperative expression of pyruvate metabolism genes to maintain a sustainable environment for population stability. MBio 7: pii: e01863-16. Abstract

Shearer AM, Rana R, Austin K, Baleja JD, Nguyen N, Bohm A, Covic L, Kuliopulos A. 2016. Targeting liver fibrosis with a cell-penetrating PAR2 pepducin. J Biol Chem. 291: 23188-23198. Abstract

Zhang P, Leger AJ, Baleja JD, Rana R, Corlin T, Nguyen N, Koukos G, Bohm A, Covic L, Kuliopulos A. 2015. Allosteric activation of a G protein coupled receptor with cell-penetrating receptor mimetics. J Biol Chem. 290: 15785-15798. Abstract

Quartararo JS, Eshelman MR, Peraro L, Yu H, Baleja JD, Lin YS, Kritzer JA. 2014. A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. Bioorg Med Chem. 22: 6387-6391.  Abstract

Kamens AJ, Eisert RJ, Corlin T, Baleja JD, Kritzer JA. 2014. Structured cyclic peptides that bind the EH domain of EHD1. Biochemistry 53: 4758-4760.  Abstract

Cherry JJ, Rietz A, Malinkevich A, Liu Y, Xie M, Bartolowits M, Davisson VJ, Baleja JD, Androphy EJ. 2013. Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 e6 function. PLoS One 8: e84506. Abstract

Liberman R, Cotter K, Baleja JD, Forgac M. 2013. Structural analysis of the N-terminal domain of subunit a of the yeast vacuolar ATPase (V-ATPase) using accessibility of single cysteine substitutions to chemical modification. J Biol Chem. 288: 22798-22808. Abstract

Krishnamurthy VM, Raman VS, Mowery RA, Hentz M, Baleja JD, Shaw BF, Kumar K. 2013. Ligand-induced protein mobility in complexes of carbonic anhydrase II and benzenesulfonamides with oligoglycine chains. PLoS One 8: e0057629. Abstract

Clark GA, Baleja JD, Kumar K. 2012. Cross-strand interactions of fluorinated amino acids in β-hairpin constructs. J Am Chem Soc. 134: 17912-17921. Abstract

Zhang P, Gruber A, Kasuda S, Kimmelstiel C, O'Callaghan K, Cox DH, Bohm A, Baleja JD, Covic L, Kuliopulos A. 2012. Suppression of arterial thrombosis without affecting hemostatic parameters with a cell-penetrating PAR1 pepducin. Circulation 126: 83091. Abstract

Moore FB, Baleja JD. 2012. Molecular remodeling mechanisms of the neural somatodendritic compartment. Biochim Biophys Acta. 1823: 1720-1730. Abstract

Nuzzio KM, Cullinan DB, Novakovic VA, Boettcher JM, Rienstra CM, Gilbert GE, Baleja JD.2012. Backbone resonance assignments of the C2 domain of coagulation factor VIII. Biomol NMR Assign. 7: 31-34. Abstract

Badway JA, Baleja JD.  2011. Reps2: A cellular signaling and molecular trafficking nexus. Int J Biochem Cell Biol. 43: 1660-1663. Abstract

Bose K, Meinke G, Bohm A, Baleja JD.  2011. Design and characterization of an enhanced repressor of human papillomavirus E2 protein. FASEB J. 25: 2354-2361. Abstract

Novakovic VA, Cullinan DC, Wakabayashi H, Fay P, Baleja JD, Gilbert GE. 2011. Membrane binding properties of the factor VIII C2 domain. Biochem J. 187-196. Abstract